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Results for “HIE”

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Research

PAEAN adds a second phase 3 no-benefit result for high-dose erythropoietin in cooled HIE

In 313 infants with moderate or severe HIE, death or moderate/severe developmental deficit occurred in 34.1% with erythropoietin and 28.7% with placebo (RR 1.19, 95% CI 0.84–1.68). Together with HEAL, PAEAN weakens the efficacy case while leaving rare-harm uncertainty.

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